BCCE 2014 Organizing Committee

General Chair
Sherril Soman
Grand Valley State University
somans@gvsu.edu

Program Chair
Julie Henderleiter
Grand Valley State University
henderlj@gvsu.edu

Exhibition/Sponsors Chair
Robert Smart
Grand Valley State University
smart@gvsu.edu

Workshop Chair
Stephanie Schaertel
Grand Valley State University
schaerts@gvsu.edu

General Papers Chair
Jessica VandenPlas
Grand Valley State University
vandenpj@gvsu.edu

General Posters Chairs
Ellen Yezierski
Miami University
yeziere@miamioh.edu

Jessica VandenPlas
Grand Valley State University
vandenpj@gvsu.edu

2YC3 Program Chair
Tom Neils
Grand Rapids Community College
tneils@grcc.edu

Publicity Chair
Tom Pentecost
Grand Valley State University
pentecot@gvsu.edu

Site Management/Local Arrangements
Sandra Bacon
Grand Valley State University
bacons@gvsu.edu

Mary Ann Sheline
Grand Valley State University
shelinem@gvsu.edu

Pre-College Program Chair
Alice Putti
Jension High School
aputti31@yahoo.com

Webmasters
Mary Karpen
Grand Valley State University
karpenm@gvsu.edu

Chris Lawrence
Grand Valley State University
lawrechi@gvsu.edu

Registration
Tracy VanderMeer
Grand Connection
tracy@grandconnection.com

Christina Thelen
Grand Connection
Christina@grandconnection.com

Administrative Support
Janet VanRhee
Grand Valley State University
vanrheej@gvsu.edu

Volunteer Coordinator
Diane Miller
Grand Valley State University
milledia@gvsu.edu

P663: Radial chromatography: An alternative to columns in the undergraduate organic lab

Author: Robert B. Miller, University of Richmond, USA

Co-Author: William S. Case, University of Richmond, USA

Date: 8/5/14

Time: 5:15 PM6:30 PM

Room: LIB

Related Symposium: S33

Separation techniques are usually presented in the undergraduate organic laboratory to teach students how to purify and isolate compounds. Often the concept of liquid chromatography is introduced by having students create “silica gel columns” to separate components of a reaction mixture. While useful, column chromatography can be a laborious technique for students to perform. The separation efficiency can be compromised if students do not prepare the column correctly, and the time required to separate substances can extend beyond a typical lab period. Herein, we discuss the use of radial chromatography as an alternative to the traditional column chromatography technique utilized in many teaching labs. Radial chromatography can be used to introduce the principles that underlie liquid chromatography, with the added benefit of providing a relatively fast and highly efficient separation. We present an experiment for the efficient separation of a mixture containing 2-nitroaniline and 3-nitroanilne using radial chromatography. Typical student results show that each substance can be collected with a high percent recovery (~70-80%). Furthermore, the melting range of each isolated substance is found to be in agreement with literature values. The separation can be completed in 20-30 minutes once the sample has been loaded.