P860a: One-pot synthesis of chalcone epoxides: A green organic chemistry experiment developed through a senior capstone project

Author: Renuka Manchanayakage, Susquehanna University, USA

Co-Author: Dalyna Ngo and Mbelu Kalala, Susquehanna University, USA

Date: 8/6/14

Time: 3:40 PM3:50 PM

Room: MAK B1120

Related Symposium: S57

In recent years, there has been an increased effort to introduce green chemistry principles into organic synthesis. One-pot multicomponent processes and one-pot consecutive processes have been discovered that allow compounds to be prepared without having to isolate and purify the intermediates, thereby minimizing the waste. As part of a senior capstone project, a one-pot synthesis for chalcone epoxides has been developed. Various chalcone epoxides can be synthesized from substituted benzaldehydes and acetophenones by one-pot consecutive reactions of aldol condensation and epoxidation. A low concentration of hydrogen peroxide can be used as the epoxidizing agent. The reaction progress can be monitored by thin layer chromatography. The functional group transformation can be studied by NMR spectroscopy.

P267: Workshop style green chemistry course for science majors [WITHDRAWN]

Author: Renuka Manchanayakage, Susquehanna University, USA

Co-Author:

Date: 8/4/14

Time: 4:00 PM4:20 PM

Room: LMH 114

Related Symposium: S7

It is important that students from various areas of science will be exposed to green chemistry as many innovative science discoveries are made today through interdisciplinary collaborative work. A Green Chemistry course was developed and offered for science majors with a unique workshop style integrating class work with laboratory activities. This approach allows the development of green chemistry concepts to move smoothly between lecture and laboratory activities and the green chemistry concepts are further discussed using laboratory results and pre- and post-lab questionnaires. This course provides students the opportunity to explore the connection between green chemistry and their local environment, and to improve their critical thinking, problem solving, oral presentation and teamwork skills.