P160: Proteopedia – a scientific ‘wiki’ bridging the rift between 3D structure and function of biomacromolecules

Author: Jaime Prilusky, Weizmann Institute of Science, Israel

Co-Author: Jaime Prilusky and Joel L. Sussman, Weizmann Institute of Science, Israel

Date: 8/4/14

Time: 9:55 AM10:15 AM

Room: LTT 102

Related Symposium: S17

Proteopedia is a wiki web resource, http://proteopedia.org, which aids in understanding of the structure/function relationship of biomacromolecules. The ‘3D’ images on each page are surrounded by descriptive text containing hyperlinks that change the appearance (view, representations, colors or labels) of the adjacent 3D structure to reflect the concept discussed in the text. This makes the complex structural information readily accessible and comprehensible, even to non-structural biologists. Using Proteopedia, scientists and students can easily create descriptions of biomacromolecules linked to their 3D structure, e.g., a page on the way inhibitors block HIV Protease, http://proteopedia.org/w/HIV-1_protease. Pages can be viewed on computers and tables via the molecular viewer JSmol. Content is being added by ~2,600 Proteopedia’s users from ~50 countries, in a dozen different languages, including Arabic, Russian &Chinese. Members of the scientific community are invited to request a Proteopedia user account, at no cost, to create and edit pages, see: http://proteopedia.org/w/Special:RequestAccount.

P160 Prilusky